Semaglutide Dosage Chart: Units, mg/mcg & Reconstitution Math
By James Li, Lead Editor · Updated · Reviewed
Quick answer
This chart converts Semaglutide between milligrams, micrograms, and syringe units, and ten units on a U-100 syringe is always 0.1 mL, while how many micrograms sit in that 0.1 mL depends on the concentration, which is vial milligrams divided by water milliliters.
Doubling the water cuts the amount in each unit in half, and the rows are round samples so the pattern is easy to see rather than amounts anyone should measure.
Blends
Optional. Extra peptides are added to the vial total.
Waiting on Input
5 mg vial, 2 mL water, 250 mcg. Example only, not a dose.
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Illustrative arithmetic only, not a recommendation. The result for Semaglutide uses only the numbers you type.
How do you read a Semaglutide unit conversion chart?
Read the table as arithmetic for Semaglutide rather than as a list of amounts to measure.
Each row starts from a sample vial and a sample water volume and then shows the concentration that division produces, ten units is always 0.1 mL on a U-100 syringe, the micrograms inside those ten units change when the water volume changes, and you put your own label numbers in the calculator when you want a mark for your vial.
How do you convert Semaglutide mg to mcg?
For Semaglutide, multiply milligrams by 1,000 to get micrograms.
That conversion does not produce a syringe mark, because units measure volume and you still divide the micrograms you want to measure by the micrograms in each milliliter.
How many syringe units equal a given Semaglutide amount?
A U-100 syringe marks 100 units per milliliter, so each unit is 0.01 mL, and that definition does not change with the barrel.
A 30-unit barrel holds 0.3 mL, a 50-unit barrel holds 0.5 mL, and a 100-unit barrel holds 1 mL, so if the calculated draw is larger than the barrel you selected it does not fit in one syringe and the calculator says so.
How does BAC water volume change concentration?
Concentration in mg/mL is the milligrams of Semaglutide divided by the milliliters of water.
There is no required volume, because more water spreads the same milligrams across more marks, which is easier to read when the amount you measure is small, while less water packs more into each unit and makes a small draw harder to see on the barrel.
Worked example: entering your own numbers into the calculator
Walk the sample in order by dividing vial milligrams by water milliliters, converting the amount you want to measure into micrograms, dividing by the concentration in mcg/mL, and then multiplying the milliliters by 100 for a U-100 mark.
These are sample numbers only and not a dose: 10 mg in 2 mL is 5 mg/mL, or 5,000 mcg/mL, and measuring 500 mcg from that mix is 0.1 mL, which is 10 units on a U-100 syringe.
Unit math
Illustrative arithmetic only. Not a dose. Barrel columns use a U-100 scale, 100 units per mL.
| Vial mg | Water mL | mg/mL | mcg/mL | mcg in 10 units |
|---|---|---|---|---|
| 10 | 2 | 5 | 5,000 | 500 |
| 5 | 1 | 5 | 5,000 | 500 |
| mL | 1 mL barrel (U-100 scale) | 0.5 mL barrel (U-100 scale) | 0.3 mL barrel (U-100 scale) |
|---|---|---|---|
| 0.05 | 5 | 5 | 5 |
| 0.1 | 10 | 10 | 10 |
| 0.25 | 25 | 25 | 25 |
| 0.5 | 50 | 50 | 50 (past barrel) |
| 1 | 100 | 100 (past barrel) | 100 (past barrel) |
FAQ
Is Semaglutide FDA approved?
Yes for Ozempic, Wegovy, and Rybelsus, while a compounded vial is not those brands.
How do I use the Semaglutide calculator?
Type the milligrams on the vial, the milliliters of water you added, and the amount you want to measure, and the syringe mark updates in the calculator.
What is BAC water?
BAC water is bacteriostatic water, which is sterile water with a preservative used to dissolve a dry vial, and the volume you add is what sets the concentration.
How many units are in 1 ml on a U-100 syringe?
On a U-100 syringe, 1 mL is 100 units, 0.5 mL is 50 units, and 0.1 mL is 10 units, provided the barrel is long enough to hold that volume.
How do I convert mg to mcg?
The matching section above goes through this in full, and the short version is to use the numbers on your own label.
Sources
- Drugs@FDA, FDA
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